Ukulawula amafutha e-visceral ngokusebenzisa i-gut microbiota (2)

I-F1-7 ithuthukisa futhi ilawula ukuhlolwa kwe-metabolic ye-glucose metabolism in vitro.

Njengoba kuboniswe emfanekisweni: I-F1-7 ne-YZX21 yanda i-GLP-1, ikhuthaza ukukhishwa kwe-insulin kuma-pancreatic β-cell kanye nokunciphisa ukukhishwa kwe-glucagon kusuka kumaseli e-pancreatic α, ngaleyo ndlela kusheshisa i-glucose metabolism.

I-F1-7 ne-YZX21 inyuse i-PYY (i-peptide YY), eyanciphisa ukuqoqwa kwe-lipid nokuthuthukisa ukumelana ne-insulin.

Ngemuva kokwengezwa kwama-probiotics, kube nokuncipha okukhulu kokubili kokuzila ukudla kweglucose yegazi kanye namazinga eglucose wegazi we-postprandial kumagundane, nomphumela ophawuleka kakhulu obonwa kushukela wegazi. I-Bifidobacteria Iqembu lezilwane F1-7. Eqenjini lokungenelela le-F1-7, i-glucose yokuzila ukudla yehla isuka ku-12.26 mmol/L yaya ku-7.13 mmol/L, emele izinga lokunciphisa lika-41.84%. Izinga likashukela we-postprandial lehla lisuka ku-24.68 mmol/L laya ku-10.95 mmol/L, ngenani lokuncipha lika-47.53%, lisondela kumazinga ajwayelekile.

Ukwengezwa nge-Bifidobacterium animalis F1-7 kanye I-Lactobacillus i-plantarum YZX21 ingathuthukisa ukuzinza kwamazinga kashukela wegazi kumagundane futhi ivimbele ukwanda okungavamile kweglucose yegazi.

Ukuhlolwa kokubekezelela i-insulin (ITT) kukhombisa ukuthi i-probiotic Bifidobacterium F1-7 ingakhuphula ngempumelelo ukuzwela kwe-insulin kumagundane. Ukuphathwa kwe-Bifidobacterium F1-7 kuholele ekwehleni kwamazinga e-insulin e-serum kusuka ku-38.42 mIU/L kuya ku-22.03 mIU/L, okubonisa ukwehla ngo-42.11%. Amazinga e-uHOMA-IR eqenjini lokungenelela le-F1-7 ehle esuka ku-17.60 aya ku-6.96, okubonisa ukwehla ngo-42.11% no-55.45%, ngokulandelana.

I-Bifidobacterium F1-7 ithuthukisa ukumelana ne-insulin futhi ilawula amazinga kashukela egazini ngokwandisa ukuzwela kwe-insulin.

Ukuncipha kwesisindo akufanele kulandelwe ngokushesha; kudinga ukubekezela nokubekezela. Ukuze unciphise ngempumelelo amafutha e-visceral anenkani, umuntu kufanele asebenzise indlela ezolile. Ngaphezu kokugcina ukudla okunempilo nsuku zonke, ukuvivinya umzimba okusesilinganisweni ukuze kukhuliswe izinga lokugayeka kokudla, ukulawula ukuphuza utshwala ukuze kuvinjelwe ukunqwabelana kwamafutha esiswini, nokwengeza ngama-probiotics ukuze kugcinwe ibhalansi ye-gut microbiota kubalulekile. Ukulungisa kancane kancane izinqubo zansuku zonke ukuze kwakhiwe indawo ezinzile evumela ukuncipha komzimba kubalulekile ekunqobeni izinselele eziqhubekayo zokukhuluphala kwamafutha e-visceral.